Brock Lesnar took home $400,000 despite losing the title to Cain Velasquez, who earned $200,000 for his main event win including a $100,000 bonus.

The official UFC 121 salaries were:

• Cain Velasquez: $200,000 (includes $100,000 win bonus) def. Brock Lesnar: $400,000
• Jake Shields: $150,000 ($75,000 win bonus) def. Martin Kampmann: $27,000
• Diego Sanchez: $100,000 ($50,000 win bonus) def. Paulo Thiago: $18,000
• Matt Hamill: $58,000 ($29,000 win bonus) def. Tito Ortiz: $250,000
• Brendan Schaub: $20,000 ($10,000 win bonus) def. Gabriel Gonzaga: $67,000
• Court McGee: $30,000 ($15,000 win bonus) def. Ryan Jensen: $10,000
• Tom Lawlor: $20,000 ($10,000 win bonus) def. Patrick Cote: $21,000
• Daniel Roberts: $16,000 ($8,000 win bonus) def. Mike Guymon: $8,000
• Sam Stout: $32,000 ($16,000 win bonus) def. Paul Taylor: $16,000
• Chris Camozzi: $16,000 ($8,000 win bonus) def. Dongi Yang: $8,000
• Jon Madsen: $16,000 ($8,000 win bonus) def. Gilbert Yvel: $30,000

The UFC 121 medical suspensions were:

• Brock Lesnar: Suspended 180 days unless cleared by ophthalmologist for possible eye injury. Minimum 60 day suspension for left cheek laceration
• Jake Shields: Suspended 180 days unless cleared by ophthalmologist for bleeding in eye and blurred vision
• Diego Sanchez: Suspended 180 days unless cleared by doctor for possible right wrist fracture
• Paulo Thiago: Suspended 60 days unless cleared by doctor for laceration
• Tito Ortiz: Suspended 45 days
• Brendan Schaub: Suspended 45 days
• Gabriel Gonzaga: Suspended 45 days
• Court McGee: Suspended 180 unless cleared by doctor for right hand fracture. Minimum 45 day suspension
• Ryan Jensen: Suspended 45 days
• Patrick Cote: Suspended 180 days unless cleared by ophthalmologist for possible eye injury
• Chris Camozzi: Suspended 60 days for left-brow laceration
• Dongi Yang: Suspended 45 days
• Gilbert Yvel: Suspended 45 days